Bulk Transcriptomics and Proteomics Analysis

Analysis of bulk tissues typically involves the isolation of RNA or protein from homogenized tissues. This provides a snapshot of the samples transcriptome or proteome which can be used to identify biomarkers associated with disease or treatment response.

What We Offer

Constellation Genomics offers analysis, interpretation, and visualisation of transcriptomic and proteomic datasets. This includes RNA-seq, Nanostring nCounter, and microarray datasets.

Every dataset is different, but some of the main methods we use include:

• Dimensional reduction of data (PCA, UMAP, TSNE)
• Differential Expression between groups
• Gene set enrichment of differentially expressed genes
• Cell type deconvolution
• Clustering of samples